Majjhima Nikaya 4:116
SUJATOYañhissa, bhikkhave, abhāvayato uppajjeyyuṁ āsavā vighātapariḷāhā, bhāvayato evaṁsa te āsavā vighātapariḷāhā na honti.
For the distressing and feverish defilements that might arise in someone who lives without developing these things do not arise when they are developed.